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Depletion of H1 promotes oncogenic and self-renewing activity within cells due to decompaction of chromatin and gene activation (Torres et al 2016)
Source E. coli
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Although baseline differences were balanced using PSM analysis in the large real-world study that showed that Tα1 significantly improved OS and PFS in patients with LUAD undergoing surgery, this is retrospective, and prospective clinical trials are still required to provide higher-level evidence-based medical evidence
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