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Activation of gut metabolite ACSL4/LPCAT3 by microplastics in drinking water mediates ferroptosis via gut–kidney axis | Communications Biology
These findings indicate that excessive S129p under pathological conditions results in gain-of-toxicity and acts as a “double-edged sword”—simultaneously promoting LB growth and impairing nuclear function
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However, GSH is found in intracellular organelles including endoplasmic reticulum (ER), nucleus, and mitochondria to control compartment-specific needs and functions (Mari et al., 2009, 2010)
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