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Within the γ-glutamyl cycle, GSH is released extracellularly, where the ectoenzyme GGT catalyzes the transfer of the γ-glutamyl group from GSH to an acceptor amino acid, generating γ-glutamyl-amino acid and cysteinylglycine
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In addition to being an antioxidant, ASC can act as a cofactor of certain oxidases, such as the 2-oxoglutarate-dependent dioxygenases (2-ODDs), and participates in the biosynthesis of several phytohormones (Prescott and John, 1996
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