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Its most consistently documented mechanism involves VEGFR2 activation and Akt-eNOS signaling, promoting angiogenesis in connective tissue research models (Hsieh et al., Journal of Molecular Medicine, 2017, DOI: 10.1007/s00109-016-1488-y)
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Continued progress in targeting glutamine metabolism for cancer therapy will likely require identification of synergistic drug combinations along with careful selection of appropriate target patient groups, which could be aided by new techniques for imaging tumor glutamine metabolism in vivo [82, 85]
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US$ 28.44
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