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Intriguingly, blocking Glu production by targeting hepatic GLS2 activity ameliorates hyperglycemia in both humans and mice, suggesting a possible new therapeutic avenue to treat hyperglycemia
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More importantly, disruptions in the intestinal barrier and imbalances in gut microbiota could further result in an increase of bacterial lipopolysaccharide and peptidoglycan at the systemic level to amplify systemic inflammation among patients with PACS persistently (Teixeira et al., 2021
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