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Utilizing proteomics, we identify elevated levels of Pin1 in preclinical AD (PCAD) brain [60], consistent with the notion that PCAD subjects, characterized by normal scores on tests of cognition but having AD-like pathology in brain, respond to elevated Aβ by increasing expression of Pin1
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The receptors most responsible for MCA include: FceR1A, FceR1B - which respond to allergens such as pollen ADGRE2 - activated by friction or scratching, resulting in red markings on the skin
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